13 Most Devastating ‘Grey’s Anatomy’ Relationship Moments, Ranked

Jeffery Dean Morgan and Katherine Heigl; Ellen Pompeo; and Sandra Oh on 'Grey's Anatomy'
ABC
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Grey’s Anatomy has left us captivated with fascinating surgeries and traumatized us with life-threatening weather events, a plane crash, a hospital shooting, and more. However, the relationships are at the core of the long-running ABC medical drama — the good, the bad, and the ugly.

Over the last 20 seasons, many romances have graced the halls of Grey Sloan, giving us plenty of moments to swoon over. While we love to root for romance, no one does heartbreak like Grey’s Anatomy.