Sophia Petrillo (Golden Girls)
Sophia (Estelle Getty), a Sicilian immigrant by way of Brooklyn, was never afraid to let anyone know when they were being a dope. Since a stroke left her without the part of the brain that handled tact, she often felt free to sling insults far and wide. If they hadn’t been so hilarious, the gals might have put her back in the retirement home that daughter Dorothy (Bea Arthur) rescued her from. Thankfully, audiences got to watch the grumpy lady’s gleeful, rapid-fire zingers for 10 years of the classic series.